Gonal-F Solution

There are many types of IVF treatment medications such as Gonal F Solution use for In Vitro Fertilization procedures. The medication used depends on the results of IVF screening (pre-screen IVF).

Gonal F Solution for Injection in Pre-Filled Pen

Gonal F Solution for Injection in Pre-Filled Pen is a type of drug manufactured in Italy used for IVF treatment. Usually, this drug is used to help produce follicles in women who cannot ovulate and do not get a significant effect from treatment with a drug called Clomiphene Citrate. The drug also helps produce some follicles in women who undergo reproductive technology assisted procedures such as in-vitro fertilization (IVF). This is a control medicine and should not be taken without a prescription from a specialist doctor who treats your fertility problems.

Gynaecology Info: Clomiphene Citrate is a medicine that you can find in pharmacies such as Clomid 50mg, Clomitop 50mg, Amicomi 100, Clomimed 50 and others. Usually, these drugs are used for first stage treatment if a woman is having infertility problems.

How Does Gonal F Medicine Work?

Gonal F is not much different from follicle hormone (FSH) which is produced naturally in the female body. This medicine will stimulate the ovaries to become large and mature. This medication can increase the risk of what is called OHSS which is Ovarian Hyperstimulation Syndrome. Excessive timulation syndrome on the ovaries results in you feeling a slight abdominal pain and bloating. These symptoms are common in patients taking Gonal F injections.

Gynaecology Info: FSH or follicle stimulating hormone is needed in the female body for the growth and development of eggs so that the fertility rate is increased.

Dream of Having Twins?

According to studies, Gonal F injection medicine can give multiple pregnancies (multiple conceive) with a higher rate than natural fertilization. So, if you crave twins, talk to your gynaecologist to get twins. But most doctors will try to reduce multiple pregnancies because a greater risk awaits mothers and unborn babies.

Warning! You are not recommended to use this drug if you have a tumor disease of the hypothalamus or pituitary gland of the brain.

Miscarriage Problems

The use of this drug can increase the frequency for miscarriage when compared to doing fertilization naturally. This is because treatment that stimulates follicle growth can bring good news for you that is pregnant and can bring bad news for you that is miscarriage.

Dosage of Gonal F to Patients for IVF

The appropriate dose to be given by a doctor depends on 2 conditions as follows: –

1. The first condition if a woman does not ovulate.
2. The second situation where women undergoing reproductive technology assistance.

The First Condition is if the Woman Does Not Ovulate

If a woman does not ovulate, you should inject Gonal F medication every day starting on the first day of the menstrual cycle until the seventh day. The recommended dose is 75-150 IU daily.

The Second Situation where Women Undergoing Reproductive Rechnology Assistance

For women who are undergoing reproductive technology assistance i.e., fertility assistance, usually the doctor will tell to make the injection on the 2^nd or 3^rd day of the menstrual cycle until the 10^th day where the follicular development has been achieved well. The recommended dose is 150-225IU per injection.

How to Inject Gonal-F

The assigned doctor, medical officer or nurse will teach you the technique of performing Gonal-F injections. The first Gonal-F injection should be under the supervision of your doctor. This medicine is multidose which needs to be injected several times according to the advice of a specialist doctor. It can be injected by yourself or your partner. You should be confident with yourself before doing the injection because each of these injections is very valuable to yourself. Proper technique can further increase the chances of getting pregnant.

Train your partner with proper injection techniques if your partner dares to do so. If your partner is scared or unsure, you are the one to inject this Gonal-F. Don’t force your partner because this IVF treatment requires high confidence and very high expectations to conceive.

Gonal-F Injection Technique

The injection site of Gonal-F is the same as if you have ever had an IUI treatment, which is an injection under the abdomen or thighs. The lower abdominal injection site is known as the subcutaneous. You cannot inject in the same place. The injection site should be changed daily to reduce reactions at the injection site such as swelling, pain, redness, rash, peeling skin and so on.

Do not inject in parts of the body that have lumps, swelling, lumps and any unwanted signs. Check the lower abdomen or thighs first before injecting. Should be stored in the refrigerator.

If There Is A Day I Forget to Inject?

Don’t panic if one day you forget to inject. Contact your doctor or medical officer and explain the matter. Do not double the dose to 2 because you forgot to inject.

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What are Gonal-F content ingredients?

Gonal-F content active ingredients: follitropin alfa, inactive ingredients: Poloxamer 188, sucrose, methionine, sodium dihydrogen phosphate monohydrate, disodium phosphate dihydrate, m-cresol, phosphoric acid, concentrated sodium hydroxide and water.

What are the side effects of Gonal-F for IVF fertility treatment?

If you notice signs such as allergies, swelling of the face, lips, tongue and other parts please tell your doctor immediately. Sneezing, shortness of breath or difficulty breathing and severe rash or itching are also other side effects that should be reported to the doctor as soon as possible. Acute side effects can also occur such as OHSS, warning signs of stroke, blood clots, rapid body warm up, headache, dizziness abdominal pain, bloated abdomen or stomach discomfort.

You can report any side effects to the National Adverse Drug Reaction Monitoring Center line at 03-78835550 or the npra.moh.gov.my website.